sample_db - Example human Rep-Seq data

Description

Example VDJ-rearranged immunoglobulin Rep-Seq sequences derived from a single individual (PGP1), sequenced on the Roche 454 platform, and thought by IMGT/V-QUEST to utilize IGHV1 family alleles.

Format

A data.frame where rows correspond to unique VDJ sequences and columns include:

  • IMGT-gapped nucleotide sequence ("SEQUENCE_IMGT")
  • IMGT/V-QUEST allele calls ("V_CALL", "D_CALL", and "J_CALL")
  • Junction length ("JUNCTION_LENGTH")

References

Gadala-Maria et al. (2015) Automated analysis of high-throughput B cell sequencing data reveals a high frequency of novel immunoglobulin V gene segment alleles. PNAS. 112(8):E862-70.