selectNovel - Select rows containing novel alleles

Description¶

selectNovel takes the result from findNovelAlleles and selects only the rows containing unique, novel alleles.

Usage¶

selectNovel(novel, keep_alleles = FALSE)

Arguments¶

novel

data.frame of the type returned by findNovelAlleles.

keep_alleles

logical indicating if different alleles leading to the same novel sequence should be kept. See Details.

Value¶

A data.frame containing only unique, novel alleles (if any) that were in the input.

Details¶

If, for instance, subject has in his genome IGHV1-2*02 and a novel allele equally close to IGHV1-2*02 and IGHV1-2*05, the novel allele may be detected by analyzing sequences that best align to either of these alleles. If keep_alleles is TRUE, both polymorphic allele calls will be retained. In the case that multiple mutation ranges are checked for the same allele, only one mutation range will be kept in the output.

Examples¶

novel <- selectNovel(SampleNovel)